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1

Loss-of-function PCSK9 mutants evade the unfolded protein response sensor, GRP78, and fail to induce endoplasmic reticulum stress when retained

Lebeau, Paul, Platko, Khrystyna, Al-Hashimi, Ali A, Byun, Jae Hyun, Lhoták, Šárka, Holzapfel, Nicholas, Gyulay, Gabriel, Igdoura, Suleiman A., Cool, David, Trigatti, Bernardo, Seidah, Nabil G., Austin

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 3.36 MB

english, 2018

2

The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice

Al-Jarallah, Aishah, Igdoura, Fatima, Zhang, Yi, Tenedero, Christine B., White, Elizabeth J., MacDonald, Melissa E., Igdoura, Suleiman A., Trigatti, Bernardo L.

Journal:

Atherosclerosis

Year:

2013

Language:

english

File:

PDF, 1.82 MB

english, 2013

3

Scavenger Class B Type 1 Knockout Mice Develop Extensive Diet-Induced Aortic Sinus and Coronary Artery Atherosclerosis in an Age-Dependent Manner

Lee, Samuel K., Fuller, Mark T., Trigatti, Bernardo L.

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 214 KB

english, 2018

4

Effects of Hematopoietic Deficiency of Pro-apoptotic Protein Bim on the Development of Atherosclerosis

Qian, Alexander S., Yu, Pei, Gonzalez, Leticia, Trigatti, Bernardo

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 165 KB

english, 2018

5

Identification of high affinity membrane-bound fatty acid-binding proteins using a photoreactive fatty acid

Gerhard E. Gerber, Dev Mangroo, Bernardo L. Trigatti

Journal:

Molecular and Cellular Biochemistry

Year:

1993

Language:

english

File:

PDF, 758 KB

english, 1993

6

Hepatic high-density lipoprotein receptors: Roles in lipoprotein metabolism and potential for therapeutic modulation

Bernardo L. Trigatti

Journal:

Current Atherosclerosis Reports

Year:

2005

File:

PDF, 508 KB

2005

7

Interleukin-15 Contributes to the Regulation of Murine Adipose Tissue and Human Adipocytes

Nicole G. Barra, Sarah Reid, Randy MacKenzie, Geoff Werstuck, Bernardo L. Trigatti, Carl Richards, Alison C. Holloway, Ali A. Ashkar

Journal:

Year:

2010

Language:

english

File:

PDF, 421 KB

english, 2010

8

Identification of Caveolin-1 as a Fatty Acid Binding Protein

Bernardo L. Trigatti, Richard G.W. Anderson, Gerhard E. Gerber

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

9

Hepatic uptake and metabolism of phosphatidylcholine associated with high density lipoproteins

Julie C. Robichaud, Jelske N. van der Veen, Zemin Yao, Bernardo Trigatti, Dennis E. Vance

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2009

Language:

english

File:

PDF, 859 KB

english, 2009

10

A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways

Aishah Al-Jarallah, Bernardo L. Trigatti

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2010

Language:

english

File:

PDF, 590 KB

english, 2010

11

Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes

Scott D. Covey, Rachelle H. Brunet, Shephali G. Gandhi, Nicole McFarlane, Douglas R. Boreham, Gerhard E. Gerber, Bernardo L. Trigatti

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 470 KB

english, 2007

12

132 Oncostatin M induces interleukin-17 receptor a and synergistic responses to interleukin-17 in mouse aortic adventitial fibroblasts

Matt Scott, Jackie Beitz, Bernardo Trigatti, Carl D. Richards

Journal:

Year:

2008

Language:

english

File:

PDF, 47 KB

english, 2008

13

PS2-04 Oncostatin M induces interleukin-1R1, interleukin-17 receptor a and synergistic responses to IL-1 and IL-17A ligands in mouse aortic adventitial fibroblasts

Matt Scott, Ali Ashkar, Bernardo Trigatti, Carl D. Richards

Journal:

Year:

2010

Language:

english

File:

PDF, 154 KB

english, 2010

14

A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency

Marc J. Champigny, Mark Mitchell, Alison Fox-Robichaud, Bernardo L. Trigatti, Suleiman A. Igdoura

Journal:

Molecular Genetics and Metabolism

Year:

2009

Language:

english

File:

PDF, 2.04 MB

english, 2009

15

67. Immune cell phenotypes and cytokine response in a mouse model of sialidase deficiency

Suleiman Igdoura, Elizabeth White, Abraham Yang, Bernardo Trigatti, Suleiman Igdoura

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

16

68. Impact of tumor necrosis factor-alpha deletion on astrolgliosis and microgliosis in the CNS of Sandhoff mice

Suleiman Igdoura, Alex Hooper, Hatim Abou-ouf, Michael Randazzo, Bernardo Trigatti

Journal:

Molecular Genetics and Metabolism

Year:

2010

Language:

english

File:

PDF, 42 KB

english, 2010

17

Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake

Bernardo L. Trigatti, Attilio Rigotti, Anne Braun

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2000

Language:

english

File:

PDF, 263 KB

english, 2000

18

Modifications in Perfringolysin O Domain 4 Alter the Cholesterol Concentration Threshold Required for Binding

Johnson, Benjamin B., Moe, Paul C., Wang, David, Rossi, Kathleen, Trigatti, Bernardo L., Heuck, Alejandro P.

Journal:

Year:

2012

Language:

english

File:

PDF, 3.18 MB

english, 2012

19

Hepatic cholesterol and bile acid metabolism and intestinal cholesterol absorption in scavenger receptor class B type I (SR-BI)-deficient mice

Pablo Mardones, Veronica Quinones, Ludwig Amigo, Mauricio Moreno, Juan F. Miquel, Margrit Schwarz, Helena E. Miettinen, Bernardo Trigatti, Monty Krieger, Sonya Vanpatten, David E. Cohen, Attilio Rigot

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 198 KB

english, 2001

20

Scavenger Receptor Class B, Type I (SR-BI) is the Major Route for the Delivery of High Density Lipoprotein Cholesterol to the Steroidogenic Pathway in Cultured Mouse Adrenocortical Cells

Ryan E. Temel, Bernardo Trigatti, Ronald B. DeMattos, Salman Azhar, Monty Krieger and David L. Williams

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.55 MB

english, 1997

21

A Targeted Mutation in the Murine Gene Encoding the High Density Lipoprotein (HDL) Receptor Scavenger Receptor Class B Type I Reveals Its Key Role in HDL Metabolism

Attilio Rigotti, Bernardo L. Trigatti, Marsha Penman, Helen Rayburn, Joachim Herz and Monty Krieger

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.67 MB

english, 1997

22

Influence of the High Density Lipoprotein Receptor SR-BI on Reproductive and Cardiovascular Pathophysiology

Bernardo Trigatti, Helen Rayburn, Marisa Viñals, Anne Braun, Helena Miettinen, Marsha Penman, Miki Hertz, Mark Schrenzel, Ludwig Amigo, Attilio Rigotti and Monty Krieger

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.50 MB

english, 1999

23

Membrane permeation and intracellular trafficking of long chain fatty acids: insights from Escherichia coli and 3T3-L1 adipocytes

Mangroo, Dev, Trigatti, Bernardo L., Gerber, Gerhard E.

Journal:

Biochemistry and Cell Biology

Year:

1995

Language:

english

File:

PDF, 1.89 MB

english, 1995

24

Fatty acid uptake in Candida tropicalis : induction of a saturable process

Trigatti, Bernardo L., Baker, Andrew D., Rajaratnam, Krishan, Rachubinski, Richard A., Gerber, Gerhard E.

Journal:

Biochemistry and Cell Biology

Year:

1992

Language:

english

File:

PDF, 714 KB

english, 1992

25

Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells

Brunet, Rachelle, How, Maxine, Trigatti, Bernardo L.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.48 MB

english, 2011

26

Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells

Schnittker, David, Kwofie, Karen, Ashkar, Ali, Trigatti, Bernardo, Richards, Carl D.

Journal:

Mediators of Inflammation

Year:

2013

Language:

english

File:

PDF, 1.35 MB

english, 2013

27

The inhibition of endocytosis affects HDL-lipid uptake mediated by the human scavenger receptor class B type I

Zhang, Yi, Ahmed, Ayesha M., Tran, Thu L., Lin, Judy, McFarlane, Nicole, Boreham, Douglas R., Igdoura, Suleiman A., Truant, Ray, Trigatti, Bernardo L.

Journal:

Molecular Membrame Biology

Year:

2007

Language:

english

File:

PDF, 2.82 MB

english, 2007

28

Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states

Lino, Marsel, Farr, Sarah, Baker, Chris, Fuller, Mark, Trigatti, Bernardo, Adeli, Khosrow

Journal:

AJP Gastrointestinal and Liver Physiology

Year:

2015

Language:

english

File:

PDF, 2.66 MB

english, 2015

29

Liver X Receptor Stimulates Cholesterol Efflux and Inhibits Expression of Proinflammatory Mediators in Human Airway Smooth Muscle Cells

Delvecchio, Christopher J., Bilan, Patricia, Radford, Katherine, Stephen, Jancy, Trigatti, Bernardo L., Cox, Gerard, Parameswaran, Krishnan, Capone, John P.

Journal:

Molecular Endocrinology

Year:

2007

Language:

english

File:

PDF, 222 KB

english, 2007

30

The role of the high-density lipoprotein receptor SR-BI in cholesterol metabolism

Trigatti, Bernardo, Rigotti, Attilio, Krieger, Monty

Journal:

Current Opinion in Lipidology

Year:

2000

Language:

english

File:

PDF, 241 KB

english, 2000

31

Myocardial Infarction Following Atherosclerosis in Murine Models

Trigatti, Bernardo, Braun, Anne, Rigotti, Attilio

Journal:

Current Drug Targets

Year:

2008

Language:

english

File:

PDF, 193 KB

english, 2008

32

Rare Genetic Variants and High-Density Lipoprotein

Trigatti, Bernardo L., Hegele, Robert A.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2016

Language:

english

File:

PDF, 739 KB

english, 2016

33

Scavenger receptor Bl - a cell surface receptor for high density lipoprotein

Rigotti, Attilio, Trigatti, Bernardo, Babitt, Jodie, Penman, Marsha, Xu, Shanghze, Krieger, Monty

Journal:

Current Opinion in Lipidology

Year:

1997

File:

PDF, 816 KB

1997

34

Characterization of Proliferating Lesion‐Resident Cells During All Stages of Atherosclerotic Growth

Lhoták, Šárka, Gyulay, Gabriel, Cutz, Jean‐Claude, Al‐Hashimi, Ali, Trigatti, Bernardo L., Richards, Carl D., Igdoura, Suleiman A., Steinberg, Gregory R., Bramson, Jonathan, Ask, Kjetil, Austin, Richa

Journal:

Journal of the American Heart Association

Year:

2016

Language:

english

File:

PDF, 5.16 MB

english, 2016

35

The effect of intracellular pH on long-chain fatty acid uptake in 3T3-L1 adipocytes: evidence that uptake involves the passive diffusion of protonated long-chain fatty acids across the plasma membrane

TRIGATTI, Bernardo L., GERBER, Gerhard E.

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 387 KB

english, 1996

36

Endoplasmic reticulum stress and Ca 2+ depletion differentially modulate the sterol-regulatory protein PCSK9 to control lipid metabolism

Lebeau, Paul, Al-Hashimi, Ali, Sood, Sudesh, Lhotak, Sarka, Yu, Pei, Gyulay, Gabriel, Pare, Guillaume, Chen, S. R. Wayne, Trigatti, Bernardo, Prat, Annik, Seidah, Nabil, Austin, Richard C

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 2.17 MB

english, 2016

37

Macrophage Apoptosis and Necrotic Core Development in Atherosclerosis: A Rapidly Advancing Field with Clinical Relevance to Imaging and Therapy

Gonzalez, Leticia, Trigatti, Bernardo Louis

Journal:

Canadian Journal of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

38

Suppression of NK and CD8 + T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease

White, Elizabeth J., Trigatti, Bernardo L., Igdoura, Suleiman A.

Journal:

Journal of Neuroimmunology

Year:

2017

Language:

english

File:

PDF, 1.88 MB

english, 2017

39

SR-B1 and PDZK1

Trigatti, Bernardo L.

Journal:

Current Opinion in Lipidology

Year:

2017

Language:

english

File:

PDF, 368 KB

english, 2017

40

HDL protects against doxorubicin induced cardiotoxicity in a scavenger receptor class B type 1, PI3K, and AKT dependent manner.

Durham, Kristina, Chathely, Kevin, Mak, Kei Cheng, Momen, Abdul, Thomas, Cyrus T, Zhao, Yuan-Yuan, MacDonald, Melissa E, Curtis, Jonathan M, Husain, Mansoor, Trigatti, Bernardo L

Journal:

American Journal of Physiology - Heart and Circulatory Physiology

Year:

2017

Language:

english

File:

PDF, 6.95 MB

english, 2017

41

Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering

Yu, Pei, Xiong, Ting, Tenedero, Christine B., Lebeau, Paul, Ni, Ran, MacDonald, Melissa E., Gross, Peter L., Austin, Richard C., Trigatti, Bernardo L.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2017

Language:

english

File:

PDF, 7.74 MB

english, 2017

42

High density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation, through SR-B1, PI3K, and AKT1 and 2

Durham, Kristina K, Chathely, Kevin M, Trigatti, Bernardo L

Journal:

Biochemical Journal

Year:

2018

Language:

english

File:

PDF, 6.34 MB

english, 2018

43

PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice

Yu, Pei, Qian, Alexander S., Chathely, Kevin M., Trigatti, Bernardo L.

Journal:

Atherosclerosis

Year:

2018

Language:

english

File:

PDF, 798 KB

english, 2018

44

SR-BI in Bone Marrow Derived Cells Protects Mice from Diet Induced Coronary Artery Atherosclerosis and Myocardial Infarction

Pei, Ying, Chen, Xing, Aboutouk, Dina, Fuller, Mark T., Dadoo, Omid, Yu, Pei, White, Elizabeth J., Igdoura, Suleiman A., Trigatti, Bernardo L., Schulz, Christian

Journal:

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

45

High Density Lipoprotein Mediated Protection of Macrophages against Apoptosis Requires Scavenger Receptor Class B Type 1 Activity and Sphingosine-1-Phosphate

Chathely, Kevin, González, Leticia, Trigatti, Bernardo L.

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 42 KB

english, 2018

46

Hepatic Cholesterol Dysregulation in SR-B1/ApoE dKO Mice

Xiong, Ting, Yu, Pei, Lebeau, Paul, Austin, Richard C., Trigatti, Bernardo L.

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 64 KB

english, 2018

47

Loss-of-function PCSK9 Mutants Evade the Unfolded Protein Response Sensor, GRP78, and Fail to Induce Endoplasmic Reticulum Stress when Retained

Lebeau, Paul, Platko, Khrystyna, Al-Hashimi, Ali, Byun, Jae Hyun, Lhotak, Sarka, Holzapfel, Nicholas, Gyulay, Gabriel, Igdoura, Suleiman A., Cool, David R., Trigatti, Bernardo, Seidah, Nabil G., Austi

Journal:

Atherosclerosis Supplements

Year:

2018

Language:

english

File:

PDF, 45 KB

english, 2018

48

Low-density lipoprotein (LDL)-dependent uptake of Gram-positive lipoteichoic acid and Gram-negative lipopolysaccharide occurs through LDL receptor

Grin, Peter M., Dwivedi, Dhruva J., Chathely, Kevin M., Trigatti, Bernardo L., Prat, Annik, Seidah, Nabil G., Liaw, Patricia C., Fox-Robichaud, Alison E.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 1.51 MB

english, 2018

49

Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice

Gonzalez, Leticia, Qian, Alexander, Tahir, Usama, Yu, Pei, Trigatti, Bernardo

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 5.58 MB

english, 2017

50

Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration and attenuates atherosclerosis in ApoE knockout mice

White, Elizabeth J, Gyulay, Gabriel, Lhoták, Šárka, Szewczyk, Magdalena M., Chong, Taryne, Fuller, Mark T, Dadoo, Omid, Fox-Robichaud, Alison E, Austin, Richard C., Trigatti, Bernardo, Igdoura, Suleim

Journal:

Journal of Biological Chemistry

Year:

2018

Language:

english

File:

PDF, 2.07 MB

english, 2018

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